Antioxidant and anti-tyrosinase activities of carissa carandas linn. fruit extracts and their applications in cosmetics
By: Thitilertdecha, N
.
Contributor(s): Pintathong, P.
Publisher: Mumbai Indian Journal of Pharmaceutical Science 2022Edition: Vol.84(5), Sep-Oct.Description: 1218-1226p.Subject(s): PHARMACEUTICSOnline resources: Click here
In:
Indian journal of pharmaceutical sciencesSummary: This study aimed to evaluate the biological properties of Carissa carandas Linn. pulp and seed extracts as
well as its efficacy in cosmetic application. The extracts of Carissa carandas pulp and seeds were analysed
for their phenolic content, antioxidant and tyrosine inhibition activities. Emulgels containing the extract
were also formulated and evaluated for safety and efficacy in the improvement on skin conditions. The
Carissa carandas seed extract contained a higher amount of phenolic content and exhibited more potential
in radical scavenging than Carissa carandas pulp extract. All extracts possessed similar potential in tyrosine
inhibition activity. The results indicated that the phenolic compounds of Carissa carandas extracts were
attributed to its radical scavenging property (R=0.998). The formulated emulgels with Carissa carandas
seed extract were stable under accelerated conditions and regarded as safe based on the irritation test. The
efficacy results proved that the Carissa carandas seed extract was effective in improving skin moisture;
transepidermal water loss, erythema and elasticity as well as lightening the skin’s color. The results
recommend that phenolic compounds of Carissa carandas extract could be utilized in cosmetics as an anti-
aging agent.
| Item type | Current location | Call number | Status | Date due | Barcode | Item holds |
|---|---|---|---|---|---|---|
Articles Abstract Database
|
School of Pharmacy Archieval Section | Not for loan | 2023-1133 |
This study aimed to evaluate the biological properties of Carissa carandas Linn. pulp and seed extracts as
well as its efficacy in cosmetic application. The extracts of Carissa carandas pulp and seeds were analysed
for their phenolic content, antioxidant and tyrosine inhibition activities. Emulgels containing the extract
were also formulated and evaluated for safety and efficacy in the improvement on skin conditions. The
Carissa carandas seed extract contained a higher amount of phenolic content and exhibited more potential
in radical scavenging than Carissa carandas pulp extract. All extracts possessed similar potential in tyrosine
inhibition activity. The results indicated that the phenolic compounds of Carissa carandas extracts were
attributed to its radical scavenging property (R=0.998). The formulated emulgels with Carissa carandas
seed extract were stable under accelerated conditions and regarded as safe based on the irritation test. The
efficacy results proved that the Carissa carandas seed extract was effective in improving skin moisture;
transepidermal water loss, erythema and elasticity as well as lightening the skin’s color. The results
recommend that phenolic compounds of Carissa carandas extract could be utilized in cosmetics as an anti-
aging agent.
Click on an image to view it in the image viewer
There are no comments for this item.